Q7K740 · 3D7 · 397 aa
N-terminusJunctionalRepeatC-terminus
Click a residue to filter. Double-click to zoom.
| Antibody | Region | Epitope observed | Footprint | VH germline | Isotype | KD | IC50 | PDB |
|---|---|---|---|---|---|---|---|---|
| 1392 Homo sapiens · wild-type | C-terminus | EPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEKC | 314-314, 317-321, 324-334, 343-343, 346-346, 350-360, 369-371 | IGHV4-4*07 | TBU | TBU | TBU | 1 |
| 1393 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1437 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1488 Homo sapiens · wild-type | C-terminus | EPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEKCS | 313-324, 327-327, 330-340, 343-347, 351-367, 370-375 | IGHV3-21*01 | TBU | TBU | TBU | 1 |
| 1502 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1504 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1512 Homo sapiens · wild-type | C-terminus | EEPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEK | 309-318, 321-322, 325-325, 331-331, 338-352, 355-356, 360-362, 365-370 | IGHV3-30*01 | TBU | TBU | TBU | 1 |
| 1525 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1534 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1550 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1710 Homo sapiens · wild-type | C-terminus | EPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEKC | 314-321, 324-324, 327-330, 338-340, 347-364, 374-374 | IGHV3-21*01 | TBU | TBU | TBU | 1 +1 apo |
| 234 Homo sapiens · wild-type | C-terminus | EPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEK | 310-310, 314-314, 317-321, 324-327, 331-331, 340-340, 345-348, 354-361, 364-370 | IGHV3-21*08 | TBU | TBU | TBU | 1 |
| 236 Homo sapiens · wild-type | C-terminus | PSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKME | 314-314, 317-333, 337-337, 343-345, 348-350, 353-360, 370-371 | IGHV3-48*01 | TBU | TBU | TBU | 1 |
| 3246 Homo sapiens · wild-type | Repeat | VDENANANSA | 293-301 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 352 Homo sapiens · wild-type | C-terminus | PSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKM | 313-314, 317-321, 324-324, 327-327, 331-333, 337-337, 343-343, 353-362, 370-371 | IGHV3-21*08 | TBU | TBU | TBU | 1 |
| 367 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 369 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 3764 Homo sapiens · wild-type | C-terminus | NMPNDPNRNV | 285-293 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 389 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 4493 Homo sapiens · wild-type | Junctional | NPDPNANPNVDPNAN | 100-115 | IGHV3-49*04 | TBU | TBU | TBU | 5 |
| 5D5 Mus musculus · wild-type | N-terminus | EDNEKLRKPKHK | 81-92 | IGHV1-81*01 | TBU | TBU | TBU | 1 |
| 668 Homo sapiens · wild-type | Junctional | GNPDPNANP | 101-108 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| 7160 Homo sapiens · wild-type | Junctional | NPNANPNANPNANPNANPNANPNANPNANPN | 101-115, 249-257, 261-272 | IGHV3-49*03 | TBU | TBU | TBU | 5 +1 apo |
| CIS42 Homo sapiens · wild-type | Junctional | NPDPNANPNVDPN | 101-113 | IGHV7-4-1*02 | TBU | TBU | TBU | 4 |
| CIS43 Homo sapiens · wild-type | Junctional | NPDPNANPNVDPN | 101-113 | IGHV1-3*01 | TBU | TBU | TBU | 4 |
| CIS43_Var10 Homo sapiens · point-variant | Junctional | NPDPNANPNVDPNA | 101-114 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| CIS43_Var2 Homo sapiens · point-variant | Junctional | NPDPNANPNVDPN | 101-113 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| iGL-CIS43.D3 Homo sapiens · germline-variant | Junctional | NPDPNANPNVDPN | 101-113 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| Ky15.1 Mus musculus · wild-type | Junctional | DGNPDPNAN | 99-106 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky15.10 Mus musculus · wild-type | Junctional | DPNANPNVDPNAN | 101-110 | IGHV3-33*01 | TBU | TBU | TBU | 3 |
| Ky15.10-Y100E/K variant Mus musculus · point-variant | Junctional | PDPNANPN | 102-109 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky15.11 Mus musculus · wild-type | Junctional | DGNPDPNANPN | 99-109 | IGHV3-33*01 | TBU | TBU | TBU | 2 |
| Ky15.11-S100I/K variant Mus musculus · point-variant | Junctional | NPDPNANPN | 101-109 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky15.2 Mus musculus · wild-type | Junctional | NVDPNANPNVD | 100-110 | IGHV3-33*03 | TBU | TBU | TBU | 5 |
| Ky15.3 Mus musculus · wild-type | Junctional | PDPNANPNVDPNA | 102-113 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky15.5 Mus musculus · wild-type | Junctional | PDPNANPNVDP | 102-112 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky15.7 Mus musculus · wild-type | Junctional | DPNANPNVDPN | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky15.8 Mus musculus · wild-type | Junctional | NPDPNANPN | 101-109 | IGHV3-33*03 | TBU | TBU | TBU | 2 |
| Ky224 Mus musculus · wild-type | Junctional | DPNANPNVDPNANP | repeat frame | IGHV3-33*03 | TBU | TBU | TBU | 1 |
| Ky311 Mus musculus · wild-type | Junctional | DGNPDPNAN | 99-106 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky315 Mus musculus · wild-type | Repeat | NVDPNANPNVD | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| L9 Homo sapiens · wild-type | Repeat | KKFSVEEENNKVTLTLCKEKTDGTVTCLTVEWEYEVNPNVDPNDQKAFKEITILSLKEMLGKNFEEFVKLNGKKLKVSIKATITSNPNVDNEVRLKVKSEDGKIFELCDMYRCDPDEPCIKTPRKCNPNVDLETIAKRTGSRVVEEEFTMNLKVEK | 26-34, 37-37, 41-43, 47-47, 50-52, 69-70, 81-81, 84-85, 105-111, 115-119, 123-130, 187-187, 191-199, 289-289, 295-295, 304-304, 323-327, 347-354, 362-363, 367-368, 373-380, 384-386 | IGHV3-33*01 | TBU | TBU | TBU | 6 +1 apo |
| m42.126 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNAN | 101-115 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m42.127 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNAN | 101-115 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.138 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNA | 101-114 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.149 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNAN | 101-115 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.151 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNA | 101-114 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.159 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNA | 101-114 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.160 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNAN | 101-115 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| MAD2-6 (IgA/IgG Fab) Homo sapiens · wild-type | N-terminus | LRKPKHKKLKQ | 86-96 | IGHV4-39*01 | TBU | TBU | TBU | 2 |
| MAD21-101 Homo sapiens · wild-type | N-terminus | EPADGNPDPNANPNVDPN | 84-84, 97-112, 397-397 | IGHV4-59*02 | TBU | TBU | TBU | 1 |
| MAD22-38 Homo sapiens · wild-type | N-terminus | EPADGNPD | 84-84, 97-101 | IGHV4-39*01 | TBU | TBU | TBU | 1 |
| MAD24-01 Homo sapiens · wild-type | N-terminus | EPADGNPD | 84-84, 97-103 | IGHV3-11*05 | TBU | TBU | TBU | 1 |
| MGG4 Homo sapiens · wild-type | Junctional | NPDPNAN | 101-106 | IGHV3-33*03 | TBU | TBU | TBU | 1 |
| P3-21 Homo sapiens · point-variant | Junctional | NPDPNANPNVDPNA | 101-114 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| P3-42 Homo sapiens · point-variant | Junctional | NPDPNANPNVDPNA | 101-111, 114-114 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| P3-43 Homo sapiens · point-variant | Junctional | NPDPNANPNVDPN | 101-113 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| sdAb1 Lama glama · wild-type | C-terminus | PSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEKCS | 313-314, 317-333, 337-337, 345-345, 351-352, 355-361, 370-373 | IGHV3-23*01 | TBU | TBU | TBU | 1 |
| sdAb9 Lama glama · wild-type | C-terminus | EPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEKCSS | 310-310, 313-314, 317-321, 324-326, 331-331, 337-340, 345-345, 351-370, 373-376 | IGHV3-23*01 | TBU | TBU | TBU | 1 |