Q7K740 · 3D7 · 397 aa
N-terminusJunctionalRepeatC-terminus
A106 · contacted by 35 of 82 mAbs
| Antibody | Region | Epitope observed | Footprint | VH germline | Isotype | KD | IC50 | PDB |
|---|---|---|---|---|---|---|---|---|
| 311 Homo sapiens · wild-type | Repeat· major | DPNANPNVDPNANPNVDPNANPNVDPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANP | 103-191 | IGHV3-33*01 | TBU | TBU | TBU | 4 |
| 356 Homo sapiens · wild-type | Repeat· major | DPNANPNVDPNANPNVDPNANPNVDPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNA | 103-190 | IGHV3-33*01 | TBU | TBU | TBU | 2 |
| 4493 Homo sapiens · wild-type | Junctional | NPDPNANPNVDPNAN | 100-115 | IGHV3-49*04 | TBU | TBU | TBU | 5 |
| 668 Homo sapiens · wild-type | Junctional | GNPDPNANP | 101-108 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| 7088 Homo sapiens · wild-type | Repeat· major | NPDPNANPNV | 101-110 | IGHV3-33*01 | TBU | TBU | TBU | 2 |
| 7160 Homo sapiens · wild-type | Junctional | NPNANPNANPNANPNANPNANPNANPNANPN | 101-115, 249-257, 261-272 | IGHV3-49*03 | TBU | TBU | TBU | 5 +1 apo |
| CIS42 Homo sapiens · wild-type | Junctional | NPDPNANPNVDPN | 101-113 | IGHV7-4-1*02 | TBU | TBU | TBU | 4 |
| CIS43 Homo sapiens · wild-type | Junctional | NPDPNANPNVDPN | 101-113 | IGHV1-3*01 | TBU | TBU | TBU | 4 |
| Ky15.1 Mus musculus · wild-type | Junctional | DGNPDPNAN | 99-106 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky15.10 Mus musculus · wild-type | Junctional | DPNANPNVDPNAN | 101-110 | IGHV3-33*01 | TBU | TBU | TBU | 3 |
| Ky15.11 Mus musculus · wild-type | Junctional | DGNPDPNANPN | 99-109 | IGHV3-33*01 | TBU | TBU | TBU | 2 |
| Ky15.2 Mus musculus · wild-type | Junctional | NVDPNANPNVD | 100-110 | IGHV3-33*03 | TBU | TBU | TBU | 5 |
| Ky15.3 Mus musculus · wild-type | Junctional | PDPNANPNVDPNA | 102-113 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky15.5 Mus musculus · wild-type | Junctional | PDPNANPNVDP | 102-112 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| Ky15.8 Mus musculus · wild-type | Junctional | NPDPNANPN | 101-109 | IGHV3-33*03 | TBU | TBU | TBU | 2 |
| Ky311 Mus musculus · wild-type | Junctional | DGNPDPNAN | 99-106 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| L9 Homo sapiens · wild-type | Repeat | KKFSVEEENNKVTLTLCKEKTDGTVTCLTVEWEYEVNPNVDPNDQKAFKEITILSLKEMLGKNFEEFVKLNGKKLKVSIKATITSNPNVDNEVRLKVKSEDGKIFELCDMYRCDPDEPCIKTPRKCNPNVDLETIAKRTGSRVVEEEFTMNLKVEK | 26-34, 37-37, 41-43, 47-47, 50-52, 69-70, 81-81, 84-85, 105-111, 115-119, 123-130, 187-187, 191-199, 289-289, 295-295, 304-304, 323-327, 347-354, 362-363, 367-368, 373-380, 384-386 | IGHV3-33*01 | TBU | TBU | TBU | 6 +1 apo |
| m42.126 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNAN | 101-115 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m42.127 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNAN | 101-115 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.138 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNA | 101-114 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.149 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNAN | 101-115 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.151 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNA | 101-114 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.159 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNA | 101-114 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| m43.160 Homo sapiens (human-Ig transgenic mouse) · wild-type | Junctional | NPDPNANPNVDPNAN | 101-115 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| MAD21-101 Homo sapiens · wild-type | N-terminus | EPADGNPDPNANPNVDPN | 84-84, 97-112, 397-397 | IGHV4-59*02 | TBU | TBU | TBU | 1 |
| MGG4 Homo sapiens · wild-type | Junctional | NPDPNAN | 101-106 | IGHV3-33*03 | TBU | TBU | TBU | 1 |