Q7K740 · 3D7 · 397 aa
N-terminusJunctionalRepeatC-terminus
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| Antibody | Region | Epitope observed | Footprint | VH germline | Isotype | KD | IC50 | PDB |
|---|---|---|---|---|---|---|---|---|
| 4498 Homo sapiens · wild-type | Repeat· major | ANPNANPNANP | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 3 |
| 7088 Homo sapiens · wild-type | Repeat· major | NPDPNANPNV | 101-110 | IGHV3-33*01 | TBU | TBU | TBU | 2 |
| 7118 Homo sapiens · wild-type | Repeat· major | NPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNAN | 110-128 | IGHV3-49*03 | TBU | TBU | TBU | 3 +1 apo |
| F10 Homo sapiens · wild-type | Repeat· minor | No structure | repeat frame | No structure | TBU | TBU | TBU | - |
| F10-heavy/L9-light chimera Homo sapiens · chimera | Repeat· major+minor | ANPNVD | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| L9 Homo sapiens · wild-type | Repeat | KKFSVEEENNKVTLTLCKEKTDGTVTCLTVEWEYEVNPNVDPNDQKAFKEITILSLKEMLGKNFEEFVKLNGKKLKVSIKATITSNPNVDNEVRLKVKSEDGKIFELCDMYRCDPDEPCIKTPRKCNPNVDLETIAKRTGSRVVEEEFTMNLKVEK | 26-34, 37-37, 41-43, 47-47, 50-52, 69-70, 81-81, 84-85, 105-111, 115-119, 123-130, 187-187, 191-199, 289-289, 295-295, 304-304, 323-327, 347-354, 362-363, 367-368, 373-380, 384-386 | IGHV3-33*01 | TBU | TBU | TBU | 6 +1 apo |
| L9-heavy/F10-light chimera Homo sapiens · chimera | Repeat· major+minor | ANPNVD | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| MAM01 (MS-1797; derived from AB-000224) Homo sapiens · engineered-unspecified | Repeat· major | ANPNANPNANPNANP | 102-114 | IGHV3-49*04 | TBU | TBU | TBU | 4 |
| MS-1805 Homo sapiens · engineered-unspecified | Repeat· major | NPDPNANPNV | 101-110 | IGHV3-33*01 | TBU | TBU | TBU | 2 |