Q7K740 · 3D7 · 397 aa
N-terminusJunctionalRepeatC-terminus
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| Antibody | Region | Epitope observed | Footprint | VH germline | Isotype | KD | IC50 | PDB |
|---|---|---|---|---|---|---|---|---|
| 1210 Homo sapiens · wild-type | Repeat· major | ANPNANPNANPNANPNANP | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 1392 Homo sapiens · wild-type | C-terminus | EPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEKC | 314-314, 317-321, 324-334, 343-343, 346-346, 350-360, 369-371 | IGHV4-4*07 | TBU | TBU | TBU | 1 |
| 1393 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1437 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1450 Homo sapiens · wild-type | Repeat· major | NANPNANPNANPNANPNAN | repeat frame | IGHV3-23*01 | TBU | TBU | TBU | 1 |
| 1488 Homo sapiens · wild-type | C-terminus | EPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEKCS | 313-324, 327-327, 330-340, 343-347, 351-367, 370-375 | IGHV3-21*01 | TBU | TBU | TBU | 1 |
| 1502 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1504 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1512 Homo sapiens · wild-type | C-terminus | EEPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEK | 309-318, 321-322, 325-325, 331-331, 338-352, 355-356, 360-362, 365-370 | IGHV3-30*01 | TBU | TBU | TBU | 1 |
| 1525 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1534 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1550 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 1710 Homo sapiens · wild-type | C-terminus | EPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEKC | 314-321, 324-324, 327-330, 338-340, 347-364, 374-374 | IGHV3-21*01 | TBU | TBU | TBU | 1 +1 apo |
| 224 (anti-NANP) Homo sapiens · wild-type | Repeat· major | NPNANPNANPNA | repeat frame | IGHV3-49*04 | TBU | TBU | TBU | 1 +2 apo |
| 2243 Homo sapiens · wild-type | Repeat· major | NPNANPNANPNANPNANP | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 227 Homo sapiens · wild-type | Repeat· major | NPNANPNANPNANPNANPNANPNANPNANPNA | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 234 Homo sapiens · wild-type | C-terminus | EPSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKMEK | 310-310, 314-314, 317-321, 324-327, 331-331, 340-340, 345-348, 354-361, 364-370 | IGHV3-21*08 | TBU | TBU | TBU | 1 |
| 236 Homo sapiens · wild-type | C-terminus | PSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKME | 314-314, 317-333, 337-337, 343-345, 348-350, 353-360, 370-371 | IGHV3-48*01 | TBU | TBU | TBU | 1 |
| 239 Homo sapiens · wild-type | Repeat· major | DPNANPNVDPNANPNVDPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNA | 111-190 | IGHV3-33*03 | TBU | TBU | TBU | 3 |
| 2541 Homo sapiens · wild-type | Repeat· major | NPNANPNANPNANPNAN | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 311 Homo sapiens · wild-type | Repeat· major | DPNANPNVDPNANPNVDPNANPNVDPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANP | 103-191 | IGHV3-33*01 | TBU | TBU | TBU | 4 |
| 311R Homo sapiens · point-variant | Repeat· major | ANPNANPNAN | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 317 Homo sapiens · wild-type | Repeat· major | NPNANPNANPNA | repeat frame | IGHV3-30*01 | TBU | TBU | TBU | 1 |
| 3246 Homo sapiens · wild-type | Repeat | VDENANANSA | 293-301 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 334 Homo sapiens · wild-type | Repeat· major | DPNANPNVDPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNA | 119-190 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 337 Homo sapiens · wild-type | Repeat· major | NPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNA | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 352 Homo sapiens · wild-type | C-terminus | PSDKHIKEYLNKIQNSLSTEWSPCSVTCGNGIQVRIKPGSANKPKDELDYANDIEKKICKM | 313-314, 317-321, 324-324, 327-327, 331-333, 337-337, 343-343, 353-362, 370-371 | IGHV3-21*08 | TBU | TBU | TBU | 1 |
| 356 Homo sapiens · wild-type | Repeat· major | DPNANPNVDPNANPNVDPNANPNVDPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNANPNA | 103-190 | IGHV3-33*01 | TBU | TBU | TBU | 2 |
| 364 Homo sapiens · wild-type | Repeat· major | NPNANPNANPNANPNANPNANPNANPNANPNANPNANPNA | repeat frame | IGHV3-33*03 | TBU | TBU | TBU | 2 |
| 366 Homo sapiens · wild-type | Repeat· major | NPNANPNANPN | repeat frame | IGHV1-2*02 | TBU | TBU | TBU | 1 |
| 367 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 369 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 3764 Homo sapiens · wild-type | C-terminus | NMPNDPNRNV | 285-293 | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 389 Homo sapiens · wild-type | C-terminus | - | repeat frame | - | TBU | TBU | TBU | 1 |
| 3945 Homo sapiens · wild-type | Repeat· major | ANPNANPNANP | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 395 Homo sapiens · wild-type | Repeat· major | NPNANP | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| 397 Homo sapiens · wild-type | Repeat· major | NPNANPNANPN | repeat frame | IGHV3-15*01 | TBU | TBU | TBU | 1 |
| 399 Homo sapiens · wild-type | Repeat· major | NPNANPNANPNANPNANPNANPNA | repeat frame | IGHV3-49*03 | TBU | TBU | TBU | 2 +1 apo |
| 580 germline Homo sapiens · germline-reverted | Repeat· major | ANPNANPN | repeat frame | IGHV3-23*01 | TBU | TBU | TBU | 1 |
| 663 Homo sapiens · wild-type | Repeat· major | ANPNANP | repeat frame | IGHV3-23*03 | TBU | TBU | TBU | 1 +1 apo |
| 667 Homo sapiens · wild-type | Repeat· major | NPNANPNA | repeat frame | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| 668 Homo sapiens · wild-type | Junctional | GNPDPNANP | 101-108 | IGHV1-3*01 | TBU | TBU | TBU | 1 |
| H.2140/K.1210 chimera Homo sapiens · chimera | Repeat· major | NANPNANPNAN | repeat frame | IGHV3-33*03 | TBU | TBU | TBU | 1 |
| MA6 Homo sapiens · wild-type | Repeat· major | NPNANPNAN | repeat frame | IGHV3-33*01 | TBU | TBU | TBU | 1 |
| MAD2-6 (IgA/IgG Fab) Homo sapiens · wild-type | N-terminus | LRKPKHKKLKQ | 86-96 | IGHV4-39*01 | TBU | TBU | TBU | 2 |
| MAD21-101 Homo sapiens · wild-type | N-terminus | EPADGNPDPNANPNVDPN | 84-84, 97-112, 397-397 | IGHV4-59*02 | TBU | TBU | TBU | 1 |
| MAD22-38 Homo sapiens · wild-type | N-terminus | EPADGNPD | 84-84, 97-101 | IGHV4-39*01 | TBU | TBU | TBU | 1 |
| MAD24-01 Homo sapiens · wild-type | N-terminus | EPADGNPD | 84-84, 97-103 | IGHV3-11*05 | TBU | TBU | TBU | 1 |